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The Subcellular Localization of the Receptor for Platelet-Activating Factor in Neutrophils Affects Signaling and Activation Characteristics

The localization in neutrophils, of the receptor for platelet-activating factor (PAFR), has been determined using subcellular fractionation and a receptor mobilization protocol. We show that the PAFR is expressed primarily in the plasma membrane. Although activation of neutrophils by PAF induces res...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Andréasson, Emil, Önnheim, Karin, Forsman, Huamei
Format: Artigo
Sprache:Inglês
Veröffentlicht: Hindawi Publishing Corporation 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3773398/
https://ncbi.nlm.nih.gov/pubmed/24069041
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2013/456407
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