GDNF-independent ureteric budding: role of PI3K-independent activation of AKT and FOSB/JUN/AP-1 signaling

A significant fraction of mice deficient in either glial cell-derived neurotrophic factor (GDNF) or its co-receptors (Gfrα1, Ret), undergoes ureteric bud (UB) outgrowth leading to the formation of a rudimentary kidney. Previous studies using the isolated Wolffian duct (WD) culture indicate that acti...

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Detalhes bibliográficos
Main Authors: Tee, James B., Choi, Yohan, Dnyanmote, Ankur, Decambre, Marvalyn, Ito, Chiharu, Bush, Kevin T., Nigam, Sanjay K.
Formato: Artigo
Idioma:Inglês
Publicado em: The Company of Biologists 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3773342/
https://ncbi.nlm.nih.gov/pubmed/24143282
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/bio.20135595
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