Robust mitotic entry is ensured by a latching switch

Cell cycle events are driven by Cyclin dependent kinases (CDKs) and by their counter-acting phosphatases. Activation of the Cdk1:Cyclin B complex during mitotic entry is controlled by the Wee1/Myt1 inhibitory kinases and by Cdc25 activatory phosphatase, which are themselves regulated by Cdk1:Cyclin...

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Bibliografiske detaljer
Main Authors: Tuck, Chloe, Zhang, Tongli, Potapova, Tamara, Malumbres, Marcos, Novák, Béla
Format: Artigo
Sprog:Inglês
Udgivet: The Company of Biologists 2013
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3773339/
https://ncbi.nlm.nih.gov/pubmed/24143279
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/bio.20135199
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