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Switches and latches: a biochemical tug-of-war between the kinases and phosphatases that control mitosis
Activation of the cyclin-dependent kinase (Cdk1) cyclin B (CycB) complex (Cdk1:CycB) in mitosis brings about a remarkable extent of protein phosphorylation. Cdk1:CycB activation is switch-like, controlled by two auto-amplification loops—Cdk1:CycB activates its activating phosphatase, Cdc25, and inhi...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Royal Society
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3203464/ https://ncbi.nlm.nih.gov/pubmed/22084385 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rstb.2011.0087 |
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