Myeloperoxidase modulates human platelet aggregation via actin cytoskeleton reorganization and store-operated calcium entry

Myeloperoxidase (MPO) is a heme-containing enzyme released from activated leukocytes into the extracellular space during inflammation. Its main function is the production of hypohalous acids that are potent oxidants. MPO can also modulate cell signaling and inflammatory responses independently of it...

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Hlavní autoři: Gorudko, Irina V., Sokolov, Alexey V., Shamova, Ekaterina V., Grudinina, Natalia A., Drozd, Elizaveta S., Shishlo, Ludmila M., Grigorieva, Daria V., Bushuk, Sergey B., Bushuk, Boris A., Chizhik, Sergey A., Cherenkevich, Sergey N., Vasilyev, Vadim B., Panasenko, Oleg M.
Médium: Artigo
Jazyk:Inglês
Vydáno: The Company of Biologists 2013
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3773338/
https://ncbi.nlm.nih.gov/pubmed/24143278
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/bio.20135314
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