Myeloperoxidase modulates human platelet aggregation via actin cytoskeleton reorganization and store-operated calcium entry

Myeloperoxidase (MPO) is a heme-containing enzyme released from activated leukocytes into the extracellular space during inflammation. Its main function is the production of hypohalous acids that are potent oxidants. MPO can also modulate cell signaling and inflammatory responses independently of it...

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Detalhes bibliográficos
Main Authors: Gorudko, Irina V., Sokolov, Alexey V., Shamova, Ekaterina V., Grudinina, Natalia A., Drozd, Elizaveta S., Shishlo, Ludmila M., Grigorieva, Daria V., Bushuk, Sergey B., Bushuk, Boris A., Chizhik, Sergey A., Cherenkevich, Sergey N., Vasilyev, Vadim B., Panasenko, Oleg M.
Formato: Artigo
Idioma:Inglês
Publicado em: The Company of Biologists 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3773338/
https://ncbi.nlm.nih.gov/pubmed/24143278
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/bio.20135314
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