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Hypoxia induces the overexpression of MicroRNA-21 in pancreatic cancer cells

BACKGROUND: Pancreatic cancer cells exist in a hypoxic microenvironment containing numerous factors which impact tumor survival, proliferation and metastasis. MicroRNAs (miRs) are differentially expressed in cancer but also altered by hypoxia. We hypothesized that hypoxia could induce miR-21 express...

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Hlavní autoři: Mace, Thomas A., Collins, Amy L., Wojcik, Sylwia E., Croce, Carlo M., Lesinski, Gregory B., Bloomston, Mark
Médium: Artigo
Jazyk:Inglês
Vydáno: 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3773267/
https://ncbi.nlm.nih.gov/pubmed/23726431
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jss.2013.04.061
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