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Hypoxia induces the overexpression of MicroRNA-21 in pancreatic cancer cells

BACKGROUND: Pancreatic cancer cells exist in a hypoxic microenvironment containing numerous factors which impact tumor survival, proliferation and metastasis. MicroRNAs (miRs) are differentially expressed in cancer but also altered by hypoxia. We hypothesized that hypoxia could induce miR-21 express...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Mace, Thomas A., Collins, Amy L., Wojcik, Sylwia E., Croce, Carlo M., Lesinski, Gregory B., Bloomston, Mark
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2013
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3773267/
https://ncbi.nlm.nih.gov/pubmed/23726431
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jss.2013.04.061
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