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Dynamics of the Meningeal CD4(+) T-cell repertoire are defined by the cervical lymph nodes and facilitate cognitive task performance in mice

The traditional view of the central nervous system (CNS) as an immune-privileged organ yielded a longstanding perception of such interactions—as seen for example in multiple sclerosis (MS) (1, 2)—as intrinsically destructive. This notion is changing with the identification of several homeostatic fun...

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Main Authors: Radjavi, Ali, Smirnov, Igor, Derecki, Noel, Kipnis, Jonathan
Formato: Artigo
Idioma:Inglês
Publicado: 2013
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3773254/
https://ncbi.nlm.nih.gov/pubmed/23752249
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mp.2013.79
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