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Profiling the Substrate Specificity of Protein Kinases by On-Bead Screening of Peptide Libraries
A robust, high-throughput method has been developed to screen one-bead-one-compound peptide libraries to systematically profile the sequence specificity of protein kinases. Its ability to provide individual sequences of the preferred substrates permits the identification of sequence contextual effec...
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| Autori principali: | , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2013
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3773219/ https://ncbi.nlm.nih.gov/pubmed/23848432 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi4008947 |
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