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Profiling the Substrate Specificity of Protein Kinases by On-Bead Screening of Peptide Libraries

A robust, high-throughput method has been developed to screen one-bead-one-compound peptide libraries to systematically profile the sequence specificity of protein kinases. Its ability to provide individual sequences of the preferred substrates permits the identification of sequence contextual effec...

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Bibliografische gegevens
Hoofdauteurs: Trinh, Thi B., Xiao, Qing, Pei, Dehua
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2013
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3773219/
https://ncbi.nlm.nih.gov/pubmed/23848432
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi4008947
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