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Crowders perturb the entropy of RNA energy landscapes to favour folding

Biological macromolecules have evolved to fold and operate in the crowded environment of the cell. We have shown previously that molecular crowding stabilizes folded RNA structures. Here we report SAXS measurements on a 64 kDa bacterial group I ribozyme in the presence of mono- and divalent ions and...

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Autores principales: Kilburn, Duncan, Roh, Joon Ho, Behrouzi, Reza, Briber, Robert M., Woodson, Sarah A.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2013
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3773054/
https://ncbi.nlm.nih.gov/pubmed/23773075
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja4030098
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