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Epsilon PKC Increases Brain Mitochondrial SIRT1 Protein Levels via Heat Shock Protein 90 following Ischemic Preconditioning in Rats

Ischemic preconditioning is a neuroprotective mechanism whereby a sublethal ischemic exposure is protective against a subsequent lethal ischemic attack. We previously demonstrated that SIRT1, a nuclear localized stress-activated deacetylase, is vital for ischemic preconditioning neuroprotection. How...

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Bibliographic Details
Main Authors: Thompson, John W., Dave, Kunjan R., Saul, Isabel, Narayanan, Srinivasan V., Perez-Pinzon, Miguel A.
Format: Artigo
Language:Inglês
Published: Public Library of Science 2013
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3772907/
https://ncbi.nlm.nih.gov/pubmed/24058702
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0075753
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