A c-Myc activation sensor-based high throughput drug screening identifies an anti-neoplastic effect of Nitazoxanide

Deregulation of c-Myc plays a central role in the tumorigenesis of many human cancers. Yet, the development of drugs regulating c-Myc activity has been challenging. To facilitate the identification of c-Myc inhibitors, we developed a molecular imaging sensor based high throughput-screening (HTS) sys...

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Hlavní autoři: Fan-Minogue, Hua, Bodapati, Sandhya, Solow-Cordero, David, Fan, Alice, Paulmurugan, Ramasamy, Massoud, Tarik F., Felsher, Dean, Gambhir, Sanjiv S.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2013
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3772774/
https://ncbi.nlm.nih.gov/pubmed/23825064
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1535-7163.MCT-12-1243
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