Sensitivity of depression-like behavior to glucocorticoids and antidepressants is independent of forebrain glucocorticoid receptors

The location of glucocorticoid receptors (GR) implicated in depression symptoms and antidepressant action remains unclear. Forebrain glucocorticoid receptor deletion on a C57B/6×129×CBA background (FBGRKO-T50) reportedly produces increased depression-like behavior and elevated glucocorticoids. We fu...

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Autores principales: Vincent, Melanie Y., Hussain, Rifat J., Zampi, Michael E., Sheeran, Katherine, Solomon, Matia B., Herman, James P., Khan, Anum, Jacobson, Lauren
Formato: Artigo
Lenguaje:Inglês
Publicado: 2013
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3772665/
https://ncbi.nlm.nih.gov/pubmed/23727405
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.brainres.2013.05.031
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