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Sensitivity of depression-like behavior to glucocorticoids and antidepressants is independent of forebrain glucocorticoid receptors

The location of glucocorticoid receptors (GR) implicated in depression symptoms and antidepressant action remains unclear. Forebrain glucocorticoid receptor deletion on a C57B/6×129×CBA background (FBGRKO-T50) reportedly produces increased depression-like behavior and elevated glucocorticoids. We fu...

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Detalhes bibliográficos
Main Authors: Vincent, Melanie Y., Hussain, Rifat J., Zampi, Michael E., Sheeran, Katherine, Solomon, Matia B., Herman, James P., Khan, Anum, Jacobson, Lauren
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3772665/
https://ncbi.nlm.nih.gov/pubmed/23727405
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.brainres.2013.05.031
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