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Sensitivity of depression-like behavior to glucocorticoids and antidepressants is independent of forebrain glucocorticoid receptors

The location of glucocorticoid receptors (GR) implicated in depression symptoms and antidepressant action remains unclear. Forebrain glucocorticoid receptor deletion on a C57B/6×129×CBA background (FBGRKO-T50) reportedly produces increased depression-like behavior and elevated glucocorticoids. We fu...

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Bibliografske podrobnosti
Main Authors: Vincent, Melanie Y., Hussain, Rifat J., Zampi, Michael E., Sheeran, Katherine, Solomon, Matia B., Herman, James P., Khan, Anum, Jacobson, Lauren
Format: Artigo
Jezik:Inglês
Izdano: 2013
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3772665/
https://ncbi.nlm.nih.gov/pubmed/23727405
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.brainres.2013.05.031
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