Role of the polycomb protein Eed in the propagation of repressive histone marks

Polycomb Group (PcG) proteins play an essential role in the epigenetic maintenance of repressive chromatin states. The gene silencing activity of the Polycomb Repressive Complex 2 (PRC2) depends on its ability to tri-methylate lysine 27 of histone H3 (H3K27) via the catalytic SET domain of the EZH2...

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Hauptverfasser: Margueron, Raphael, Justin, Neil, Ohno, Katsuhito, Sharpe, Miriam L, Son, Jinsook, Drury, William J, Voigt, Philipp, Martin, Stephen, Taylor, William R., De Marco, Valeria, Pirrotta, Vincenzo, Reinberg, Danny, Gamblin, Steven J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2009
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3772642/
https://ncbi.nlm.nih.gov/pubmed/19767730
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature08398
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