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Unfoldase-mediated protein translocation through an α-hemolysin nanopore

Using nanopores to sequence biopolymers was proposed more than a decade ago(1). Recent advances in enzyme-based control of DNA translocation(2) and in DNA nucleotide resolution using modified biological pores(3) have satisfied two technical requirements of a functional nanopore DNA sequencing device...

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Autori principali: Nivala, Jeff, Marks, Douglas B, Akeson, Mark
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3772521/
https://ncbi.nlm.nih.gov/pubmed/23376966
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nbt.2503
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