Ex vivo expansion of tumor specific lymphocytes with IL-15 and IL-21 for adoptive immunotherapy in melanoma

Although T Central Memory cells have been described as the most effective T-cell subtype against tumor growth, little is known about the requirements needed for their optimal ex vivo generation. Hence, our goal is to establish a protocol that will lead to consistent ex vivo generation of lymphocytes...

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Bibliographische Detailangaben
Hauptverfasser: Huarte, Eduardo, Fisher, Jan, Turk, Mary Jo, Mellinger, Diane, Foster, Cathy, Wolf, Benita, Meehan, Kenneth R., Fadul, Camilo E., Ernstoff, Marc S.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2009
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3772508/
https://ncbi.nlm.nih.gov/pubmed/19501956
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.canlet.2009.05.003
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