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Cell Density Plays a Critical Role in Ex Vivo Expansion of T Cells for Adoptive Immunotherapy

The successful ex vivo expansion of a large numbers of T cells is a prerequisite for adoptive immunotherapy. In this study, we found that cell density had important effects on the process of expansion of T cells in vitro. Resting T cells were activated to expand at high cell density but failed to be...

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Hlavní autoři: Ma, Qiangzhong, Wang, Yawen, Lo, Agnes Shuk-Yee, Gomes, Erica M., Junghans, Richard P.
Médium: Artigo
Jazyk:Inglês
Vydáno: Hindawi Publishing Corporation 2010
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2896674/
https://ncbi.nlm.nih.gov/pubmed/20625484
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2010/386545
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