Caspase-6 activity predicts lower episodic memory ability in aged individuals

Caspase-6 (Casp6), a cysteinyl protease that induces axonal degeneration, is activated early in Alzheimer Disease (AD) brains. To determine whether Casp6 activation is responsible for early cognitive impairment, we investigated the abundance of Casp6 activity, paired helical filament–1 (PHF-1) phosp...

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Bibliographic Details
Main Authors: Ramcharitar, Jasmine, Afonso, Veronica M., Albrecht, Steffen, Bennett, David A., LeBlanc, Andrea C.
Format: Artigo
Language:Inglês
Published: 2013
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3772349/
https://ncbi.nlm.nih.gov/pubmed/23402898
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neurobiolaging.2013.01.007
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