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A model-based prediction of the calcium responses in the striatal synaptic spines depending on the timing of cortical and dopaminergic inputs and post-synaptic spikes

The dopamine-dependent plasticity of the cortico-striatal synapses is considered as the cellular mechanism crucial for reinforcement learning. The dopaminergic inputs and the calcium responses affect the synaptic plasticity by way of the signaling cascades within the synaptic spines. The calcium con...

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Detalhes bibliográficos
Main Authors: Nakano, Takashi, Yoshimoto, Junichiro, Doya, Kenji
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3772324/
https://ncbi.nlm.nih.gov/pubmed/24062681
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncom.2013.00119
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