Dysregulated humoral immunity to nontyphoidal Salmonella in HIV-infected African adults

Nontyphoidal Salmonellae are a major cause of life-threatening bacteremia among HIV-infected individuals. Although cell-mediated immunity controls intracellular infection, antibody protects against Salmonella bacteremia. We report that high titer antibodies specific for Salmonella lipopolysaccharide...

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Main Authors: MacLennan, Calman A., Gilchrist, James J., Gordon, Melita A., Cunningham, Adam F., Cobbold, Mark, Goodall, Margaret, Kingsley, Robert A., van Oosterhout, Joep J. G., Msefula, Chisomo L., Mandala, Wilson L., Leyton, Denisse L., Marshall, Jennifer L., Gondwe, Esther N., Bobat, Saeeda, López-Macías, Constantino, Doffinger, Rainer, Henderson, Ian R., Zijlstra, Eduard E., Dougan, Gordon, Drayson, Mark T., MacLennan, Ian C. M., Molyneux, Malcolm E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3772309/
https://ncbi.nlm.nih.gov/pubmed/20413503
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1180346
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