The cardioprotective effects of urocortin are mediated via activation of the Src tyrosine kinase-STAT3 pathway

Src tyrosine kinase family was recently identified as a novel upstream modulator of MAP kinase subfamily, p42/p44, whose activation is required for urocortin (Ucn)-mediated cardioprotection. Src kinase was also shown to reduce apoptosis in different cancer cell lines, enhancing phosphorylation and D...

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Autori principali: Chen-Scarabelli, Carol, Saravolatz II, Louis, Mccaukey, Roy, Scarabelli, Gabriele, Di Rezze, Justin, Mohanty, Bibhu, Barry, Sean, Latchman, David, Georgiadis, Vassilis, McCormick, James, Saravolatz, Louis, Knight, Richard, Faggian, Giuseppe, Narula, Jagat, Stephanou, Anastasis, Scarabelli, Tiziano M
Natura: Artigo
Lingua:Inglês
Pubblicazione: Landes Bioscience 2013
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Research Paper
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3772114/
https://ncbi.nlm.nih.gov/pubmed/24069562
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/jkst.24812
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