The cardioprotective effects of urocortin are mediated via activation of the Src tyrosine kinase-STAT3 pathway

Src tyrosine kinase family was recently identified as a novel upstream modulator of MAP kinase subfamily, p42/p44, whose activation is required for urocortin (Ucn)-mediated cardioprotection. Src kinase was also shown to reduce apoptosis in different cancer cell lines, enhancing phosphorylation and D...

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Detalhes bibliográficos
Principais autores: Chen-Scarabelli, Carol, Saravolatz II, Louis, Mccaukey, Roy, Scarabelli, Gabriele, Di Rezze, Justin, Mohanty, Bibhu, Barry, Sean, Latchman, David, Georgiadis, Vassilis, McCormick, James, Saravolatz, Louis, Knight, Richard, Faggian, Giuseppe, Narula, Jagat, Stephanou, Anastasis, Scarabelli, Tiziano M
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2013
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3772114/
https://ncbi.nlm.nih.gov/pubmed/24069562
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/jkst.24812
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