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Computational Optogenetics: Empirically-Derived Voltage- and Light-Sensitive Channelrhodopsin-2 Model

Channelrhodospin-2 (ChR2), a light-sensitive ion channel, and its variants have emerged as new excitatory optogenetic tools not only in neuroscience, but also in other areas, including cardiac electrophysiology. An accurate quantitative model of ChR2 is necessary for in silico prediction of the resp...

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Bibliografske podrobnosti
Main Authors: Williams, John C., Xu, Jianjin, Lu, Zhongju, Klimas, Aleksandra, Chen, Xuxin, Ambrosi, Christina M., Cohen, Ira S., Entcheva, Emilia
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2013
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3772068/
https://ncbi.nlm.nih.gov/pubmed/24068903
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1003220
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