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Computational Optogenetics: Empirically-Derived Voltage- and Light-Sensitive Channelrhodopsin-2 Model

Channelrhodospin-2 (ChR2), a light-sensitive ion channel, and its variants have emerged as new excitatory optogenetic tools not only in neuroscience, but also in other areas, including cardiac electrophysiology. An accurate quantitative model of ChR2 is necessary for in silico prediction of the resp...

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Detalhes bibliográficos
Main Authors: Williams, John C., Xu, Jianjin, Lu, Zhongju, Klimas, Aleksandra, Chen, Xuxin, Ambrosi, Christina M., Cohen, Ira S., Entcheva, Emilia
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3772068/
https://ncbi.nlm.nih.gov/pubmed/24068903
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1003220
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