Growth factor independent-1 Maintains Notch1-Dependent Transcriptional Programming of Lymphoid Precursors

Growth factor independent 1 (Gfi1) is a transcriptional repressor originally identified as a gene activated in T-cell leukemias induced by Moloney-murine-leukemia virus infection. Notch1 is a transmembrane receptor that is frequently mutated in human T-cell acute lymphoblastic leukemia (T-ALL). Gfi1...

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Detalhes bibliográficos
Main Authors: Phelan, James D., Saba, Ingrid, Zeng, Hui, Kosan, Christian, Messer, Malynda S., Olsson, H. Andre, Fraszczak, Jennifer, Hildeman, David A., Aronow, Bruce J., Möröy, Tarik, Grimes, H. Leighton
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3772063/
https://ncbi.nlm.nih.gov/pubmed/24068942
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1003713
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