Fenretinide Corrects the Imbalance between Omega-6 to Omega-3 Polyunsaturated Fatty Acids and Inhibits Macrophage Inflammatory Mediators via the ERK Pathway

We previously identified Fragile X-related protein 1 (FXR1) as an RNA-binding protein involved in the post-transcriptional control of TNF and other cytokines in macrophages. Macrophages derived from FXR1-KO mice overexpress several inflammatory cytokines including TNF. Recently, we showed that fenre...

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Bibliografiske detaljer
Main Authors: Lachance, Claude, Wojewodka, Gabriella, Skinner, Tom A. A., Guilbault, Claudine, De Sanctis, Juan B., Radzioch, Danuta
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2013
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3771966/
https://ncbi.nlm.nih.gov/pubmed/24069363
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0074875
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