JAM-A associates with ZO-2, afadin, and PDZ-GEF1 to activate Rap2c and regulate epithelial barrier function

Intestinal barrier function is regulated by epithelial tight junctions (TJs), structures that control paracellular permeability. Junctional adhesion molecule-A (JAM-A) is a TJ-associated protein that regulates barrier; however, mechanisms linking JAM-A to epithelial permeability are poorly understoo...

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Hlavní autoři: Monteiro, Ana C., Sumagin, Ronen, Rankin, Carl R., Leoni, Giovanna, Mina, Michael J., Reiter, Dirk M., Stehle, Thilo, Dermody, Terence S., Schaefer, Stacy A., Hall, Randy A., Nusrat, Asma, Parkos, Charles A.
Médium: Artigo
Jazyk:Inglês
Vydáno: The American Society for Cell Biology 2013
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3771947/
https://ncbi.nlm.nih.gov/pubmed/23885123
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E13-06-0298
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