A Minimal Set of Tissue-Specific Hypomethylated CpGs Constitute Epigenetic Signatures of Developmental Programming

BACKGROUND: Cell specific states of the chromatin are programmed during mammalian development. Dynamic DNA methylation across the developing embryo guides a program of repression, switching off genes in most cell types. Thus, the majority of the tissue specific differentially methylated sites (TS-DM...

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Main Authors: Colaneri, Alejandro, Wang, Tianyuan, Pagadala, Vijayakanth, Kittur, Jaya, Staffa, Nickolas G., Peddada, Shyamal D., Isganaitis, Elvira, Patti, Mary Elizabeth, Birnbaumer, Lutz
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3771925/
https://ncbi.nlm.nih.gov/pubmed/24069155
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0072670
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