Bacterial Clearance Is Improved in Septic Mice by Platelet-Activating Factor-Acetylhydrolase (PAF-AH) Administration

Current evidence indicates that dysregulation of the host inflammatory response to infectious agents is central to the mortality of patients with sepsis. Strategies to block inflammatory mediators such as PAF have been investigated as adjuvant therapies for sepsis. PAF-AH, the enzyme responsible for...

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Autors principals: Teixeira-da-Cunha, Mariana G. A., Gomes, Rachel N., Roehrs, Nathassia, Bozza, Fernando A., Prescott, Stephen M., Stafforini, Diana, Zimmerman, Guy A., Bozza, Patricia T., Castro-Faria-Neto, Hugo C.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2013
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3771912/
https://ncbi.nlm.nih.gov/pubmed/24069320
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0074567
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