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PAF-acetylhydrolase expressed during megakaryocyte differentiation inactivates PAF-like lipids

Platelet activating factor (PAF) and PAF-like lipids induce inflammatory responses in target cells. These lipid mediators are inactivated by PAF-acetylhydrolase (PAF-AH). The PAF signaling system affects the growth of hematopoietic CD34(+) cells, but roles for PAF-AH in this process are unknown. Her...

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Detalhes bibliográficos
Main Authors: Foulks, Jason M., Marathe, Gopal K., Michetti, Noemi, Stafforini, Diana M., Zimmerman, Guy A., McIntyre, Thomas M., Weyrich, Andrew S.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2710923/
https://ncbi.nlm.nih.gov/pubmed/19395675
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2008-11-186312
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