Xanthohumol ameliorates atherosclerotic plaque formation, hypercholesterolemia, and hepatic steatosis in ApoE-deficient mice

SCOPE: Xanthohumol (XN), a prenylated antioxidative and anti-inflammatory chalcone from hops, exhibits positive effects on lipid and glucose metabolism. Based on its favorable biological properties, we investigated whether XN attenuates atherosclerosis in western-type diet-fed apolipoprotein-E-defic...

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Autors principals: Doddapattar, Prakash, Radović, Branislav, Patankar, Jay V., Obrowsky, Sascha, Jandl, Katharina, Nusshold, Christoph, Kolb, Dagmar, Vujić, Nemanja, Doshi, Lalit, Chandak, Prakash G., Goeritzer, Madeleine, Ahammer, Helmut, Hoefler, Gerald, Sattler, Wolfgang, Kratky, Dagmar
Format: Artigo
Idioma:Inglês
Publicat: 2013
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3771820/
https://ncbi.nlm.nih.gov/pubmed/23650230
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mnfr.201200794
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