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Subretinal Gene Therapy of Mice With Bardet-Biedl Syndrome Type 1
PURPOSE. To study safety and efficacy of subretinal adeno-associated virus (AAV) vector AAV-Bbs1 injection for treatment of a mouse model of Bardet-Biedl syndrome type 1 (BBS1). METHODS. Constructs containing a wild-type (WT) Bbs1 gene with and without a FLAG tag in AAV2/5 vectors were generated. Vi...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Association for Research in Vision and Ophthalmology
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3771708/ https://ncbi.nlm.nih.gov/pubmed/23900607 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.13-11673 |
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