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Selective autophagy degrades DICER and AGO2 and regulates miRNA activity

Micro (mi)RNAs form a class of short RNAs (~21 nt) that post-transcriptionally regulate partially complementary messenger (m)RNAs. Each miRNA may target tens-to-hundreds of transcripts to control key biological processes. While the biochemical reactions underpinning miRNA biogenesis and activity are...

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Bibliographische Detailangaben
Hauptverfasser: Gibbings, Derrick, Mostowy, Serge, Jay, Florence, Schwab, Yannick, Cossart, Pascale, Voinnet, Olivier
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3771578/
https://ncbi.nlm.nih.gov/pubmed/23143396
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncb2611
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