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Knockdown of neurokinin-1 receptor expression by small interfering RNA prevents the development of allergic rhinitis in rats

OBJECTIVE AND DESIGN: This study is aimed at exploring the role of neurokinin-1 receptor (NK-1R) in the development of allergic rhinitis (AR) in rats. METHODS: Sprague–Dawley rats were sensitized and challenged with ovalbumin to induce AR. The rats were treated intranasally with saline, control, or...

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Detalhes bibliográficos
Main Authors: Wang, Hong, Zhang, Ruxin, Wu, Jing, Hu, Hua
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Basel 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3771433/
https://ncbi.nlm.nih.gov/pubmed/23934070
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00011-013-0649-5
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