Prognostic Significance of MTOR Pathway Component Expression in Neuroendocrine Tumors

PURPOSE: Clinical studies have implicated the mechanistic target of rapamycin (serine/threonine kinase; MTOR) pathway in the regulation of neuroendocrine tumor (NET) growth. We explored whether expression of MTOR pathway components has prognostic significance in NET patients. PATIENTS AND METHODS: W...

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Detalhes bibliográficos
Main Authors: Qian, Zhi Rong, Ter-Minassian, Monica, Chan, Jennifer A., Imamura, Yu, Hooshmand, Susanne M., Kuchiba, Aya, Morikawa, Teppei, Brais, Lauren K., Daskalova, Anastassia, Heafield, Rachel, Lin, Xihong, Christiani, David C., Fuchs, Charles S., Ogino, Shuji, Kulke, Matthew H.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Clinical Oncology 2013
Assuntos:
ORIGINAL REPORTS
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3770868/
https://ncbi.nlm.nih.gov/pubmed/23980085
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1200/JCO.2012.46.6946
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