Multipotent stromal cells alleviate inflammation, neuropathology, and symptoms associated with globoid cell leukodystrophy in the twitcher mouse

Globoid cell leukodystrophy (GLD) is a common neurodegenerative lysosomal storage disorder caused by a deficiency in galactocerebrosidase (GALC), an enzyme that cleaves galactocerebroside during myelination. Bone marrow transplantation has shown promise when administered to late-onset GLD patients....

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Détails bibliographiques
Auteurs principaux: Scruggs, Brittni A., Zhang, Xiujuan, Bowles, Annie C., Gold, Peter A., Semon, Julie A., Fisher-Perkins, Jeanne M., Zhang, Shijia, Bonvillain, Ryan W., Myers, Leann, Li, Su Chen, Kalueff, Allan V., Bunnell, Bruce A.
Format: Artigo
Langue:Inglês
Publié: 2013
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3770764/
https://ncbi.nlm.nih.gov/pubmed/23606584
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/stem.1397
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