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High-throughput screening of stem cell therapy for globoid cell leukodystrophy using automated neurophenotyping of twitcher mice
Globoid cell leukodystrophy (Krabbe’s disease) is an autosomal recessive neurodegenerative disorder that results from the deficiency of galactosylceramidase, a lysosomal enzyme involved in active myelination. Due to the progressive, lethal nature of this disease and the limited treatment options ava...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3482265/ https://ncbi.nlm.nih.gov/pubmed/22951180 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbr.2012.08.020 |
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