Activation of NFAT signaling establishes a tumorigenic microenvironment through cell autonomous and non-cell autonomous mechanisms

NFAT upregulation has been linked to cellular transformation intrinsically, but it is unclear whether and how tissue cells with NFAT activation change the local environment for tumor initiation and progression. Direct evidence showing NFAT activation initiates primary tumor formation in vivo is also...

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Hoofdauteurs: Tripathi, Piyush, Wang, Yinqiu, Coussens, Matthew, Manda, Kalyan R., Casey, Adam M., Lin, Congxing, Poyo, Edward, Pfeifer, John D., Basappa, Nisha, Bates, Carlton M., Ma, Liang, Zhang, Hong, Pan, Minggui, Ding, Li, Chen, Feng
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2013
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3770739/
https://ncbi.nlm.nih.gov/pubmed/23624921
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2013.132
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