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Stochastic Stabilization of Phenotypic States: The Genetic Bistable Switch as a Case Study

We study by means of analytical calculation and stochastic simulations how intrinsic noise modifies the bifurcation diagram of gene regulatory processes that can be effectively described by the Langevin formalism. In a general context, our study raises the intriguing question of how biochemical fluc...

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Detalhes bibliográficos
Main Authors: Weber, Marc, Buceta, Javier
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3770683/
https://ncbi.nlm.nih.gov/pubmed/24039958
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0073487
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