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Identification of Potent and Selective Diphenylpropanamide RORγ Inhibitors
[Image: see text] Retinoic acid-related orphan receptor RORγt plays a pivotal role in the differentiation of T(H)17 cells. Antagonizing RORγt transcriptional activity is a potential means to treat T(H)17-related autoimmune diseases. Herein, we describe the identification of a series of diphenylpropa...
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| Główni autorzy: | , , , , , , , , , , |
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| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
American
Chemical Society
2012
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| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3770298/ https://ncbi.nlm.nih.gov/pubmed/24040486 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ml300286h |
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