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BH3 profiling – measuring integrated function of the mitochondrial apoptotic pathway to predict cell fate decisions

Apoptosis is a form of programmed cell death that is controlled at the mitochondrion by the BCL-2 family of proteins. While much has been learned about the structure and function of these proteins over the past two decades, the important goal of predicting cell fate decisions in response to toxic st...

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Detalhes bibliográficos
Main Authors: Moore, Victoria Del Gaizo, Letai, Anthony
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3770266/
https://ncbi.nlm.nih.gov/pubmed/22230093
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.canlet.2011.12.021
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