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BH3 profiling – measuring integrated function of the mitochondrial apoptotic pathway to predict cell fate decisions

Apoptosis is a form of programmed cell death that is controlled at the mitochondrion by the BCL-2 family of proteins. While much has been learned about the structure and function of these proteins over the past two decades, the important goal of predicting cell fate decisions in response to toxic st...

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Autors principals: Moore, Victoria Del Gaizo, Letai, Anthony
Format: Artigo
Idioma:Inglês
Publicat: 2012
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3770266/
https://ncbi.nlm.nih.gov/pubmed/22230093
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.canlet.2011.12.021
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