Sex Dependent Influence of a Functional Polymorphism in Steroid 5-α-Reductase Type 2 (SRD5A2) on Post-Traumatic Stress Symptoms

A non-synonymous, single nucleotide polymorphism (SNP) in the gene coding for steroid 5-α-reductase type 2 (SRD5A2) is associated with reduced conversion of testosterone to dihydrotestosterone (DHT). Because SRD5A2 participates in the regulation of testosterone and cortisol metabolism, hormones show...

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Hlavní autoři: Gillespie, Charles F., Almli, Lynn M., Smith, Alicia K., Bradley, Bekh, Kerley, Kimberly, Crain, Daniel F., Mercer, Kristina B., Weiss, Tamara, Phifer, Justine, Tang, Yilang, Cubells, Joseph F., Binder, Elisabeth B., Conneely, Karen N., Ressler, Kerry J.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2013
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3770127/
https://ncbi.nlm.nih.gov/pubmed/23505265
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ajmg.b.32147
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