Sex Dependent Influence of a Functional Polymorphism in Steroid 5-α-Reductase Type 2 (SRD5A2) on Post-Traumatic Stress Symptoms

A non-synonymous, single nucleotide polymorphism (SNP) in the gene coding for steroid 5-α-reductase type 2 (SRD5A2) is associated with reduced conversion of testosterone to dihydrotestosterone (DHT). Because SRD5A2 participates in the regulation of testosterone and cortisol metabolism, hormones show...

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Detalhes bibliográficos
Main Authors: Gillespie, Charles F., Almli, Lynn M., Smith, Alicia K., Bradley, Bekh, Kerley, Kimberly, Crain, Daniel F., Mercer, Kristina B., Weiss, Tamara, Phifer, Justine, Tang, Yilang, Cubells, Joseph F., Binder, Elisabeth B., Conneely, Karen N., Ressler, Kerry J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3770127/
https://ncbi.nlm.nih.gov/pubmed/23505265
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ajmg.b.32147
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