Ex Vivo Restimulation of Human PBMC Expands a CD3(+)CD4(−)CD8(−) γδ (+) T Cell Population That Can Confound the Evaluation of CD4 and CD8 T Cell Responses to Vaccination

The measurement of vaccine-induced humoral and CD4(+) and CD8(+) cellular immune responses represents an important correlate of vaccine efficacy. Accurate and reliable assays evaluating such responses are therefore critical during the clinical development phase of vaccines. T cells play a pivotal ro...

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Detalhes bibliográficos
Main Authors: Sedgmen, B. J., Papalia, L., Wang, L., Dyson, A. R., McCallum, H. A., Simson, C. M., Pearse, M. J., Maraskovsky, E., Hung, D., Eomois, P. P., Hartel, G., Barnden, M. J., Rockman, S. P.
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3770040/
https://ncbi.nlm.nih.gov/pubmed/24066003
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2013/186420
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