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Antibodies to human IL-10 neutralize ebvIL-10-mediated cytokine suppression but have no effect on cmvIL-10 activity

Interleukin-10 is a pivotal determinant of virus clearance or persistence. Two human herpesviruses, Epstein–Barr virus (EBV) and human cytomegalovirus (HCMV) are unique among persistent viruses because they not only trigger production of host IL-10, but both viruses also encode homologs of IL-10 tha...

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Autori principali: Brodeur, Noelle D., Spencer, Juliet V.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3769974/
https://ncbi.nlm.nih.gov/pubmed/20728483
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virusres.2010.08.012
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