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Optimization of clavulanic acid production by Streptomyces daufpe 3060 by response surface methodology
Clavulanic acid is a ß-lactam antibiotic which has a potent ß-lactamase inhibiting activity. In order to optimize its production by the new isolate Streptomyces DAUFPE 3060, the influence of two independent variables, temperature and soybean flour concentration, on clavulanic acid and biomass concen...
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| Główni autorzy: | , , , , , , |
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| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
Sociedade Brasileira de Microbiologia
2011
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3769858/ https://ncbi.nlm.nih.gov/pubmed/24031677 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1590/S1517-838220110002000030 |
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