Optimization of clavulanic acid production by Streptomyces daufpe 3060 by response surface methodology

Clavulanic acid is a ß-lactam antibiotic which has a potent ß-lactamase inhibiting activity. In order to optimize its production by the new isolate Streptomyces DAUFPE 3060, the influence of two independent variables, temperature and soybean flour concentration, on clavulanic acid and biomass concen...

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Main Authors: Marques, Daniela A. Viana, Cunha, Márcia N. Carneiro, Araújo, Janete M., Lima-Filho, José L., Converti, Attilio, Pessoa-Jr, Adalberto, Porto, Ana L. Figueiredo
Format: Artigo
Jezik:Inglês
Izdano: Sociedade Brasileira de Microbiologia 2011
Teme:
Industrial Microbiology
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3769858/
https://ncbi.nlm.nih.gov/pubmed/24031677
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1590/S1517-838220110002000030
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